TFII-I (phospho Tyr248) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611101
- 产品信息
商品描述
靶点-Target
TFII-I
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
115kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TFII-I around the phosphorylation site of Tyr248. AA range:214-263
特异性
Phospho-TFII-I (Y248) Polyclonal Antibody detects endogenous levels of TFII-I protein only when phosphorylated at Y248.
基因名称
GTF2I
蛋白名称
General transcription factor II-I
别名
GTF2I;BAP135;WBSCR6;General transcription factor II-I;GTFII-I;TFII-I;Bruton tyrosine kinase-associated protein 135;BAP-135;BTK-associated protein 135;SRF-Phox1-interacting protein;SPIN;Williams-Beuren syndrome chromosomal region
Organism-1
Human
基因ID-1
2969
SwissProt-1
P78347
Organism-2
Mouse
基因ID-2
14886
SwissProt-2
Q9ESZ8
Organism-3
Rat
基因ID-3
353256
SwissProt-3
Q5U2Y1
背景
general transcription factor IIi(GTF2I) Homo sapiens This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2013],
细胞定位
Cytoplasm . Nucleus . Colocalizes with BTK in the cytoplasm.





