TFII-I (phospho Tyr248) Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2611101

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商品描述
  • 靶点-Target

    TFII-I

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    115kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human TFII-I around the phosphorylation site of Tyr248. AA range:214-263

  • 特异性

    Phospho-TFII-I (Y248) Polyclonal Antibody detects endogenous levels of TFII-I protein only when phosphorylated at Y248.

  • 基因名称

    GTF2I

  • 蛋白名称

    General transcription factor II-I

  • 别名

    GTF2I;BAP135;WBSCR6;General transcription factor II-I;GTFII-I;TFII-I;Bruton tyrosine kinase-associated protein 135;BAP-135;BTK-associated protein 135;SRF-Phox1-interacting protein;SPIN;Williams-Beuren syndrome chromosomal region

  • Organism-1

    Human

  • 基因ID-1

    2969

  • SwissProt-1

    P78347

  • Organism-2

    Mouse

  • 基因ID-2

    14886

  • SwissProt-2

    Q9ESZ8

  • Organism-3

    Rat

  • 基因ID-3

    353256

  • SwissProt-3

    Q5U2Y1

  • 背景

    general transcription factor IIi(GTF2I) Homo sapiens This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2013],

  • 细胞定位

    Cytoplasm . Nucleus . Colocalizes with BTK in the cytoplasm.