IκB-β (phospho Thr19) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611081
- 产品信息
商品描述
靶点-Target
IκB β
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
37kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human IkappaB-beta around the phosphorylation site of Thr19. AA range:4-53
特异性
Phospho-IκB-β (T19) Polyclonal Antibody detects endogenous levels of IκB-β protein only when phosphorylated at T19.
基因名称
NFKBIB
蛋白名称
NF-kappa-B inhibitor beta
别名
NFKBIB;IKBB;TRIP9;NF-kappa-B inhibitor beta;NF-kappa-BIB;I-kappa-B-beta;IkB-B;IkB-beta;IkappaBbeta;Thyroid receptor-interacting protein 9;TR-interacting protein 9;TRIP-9
Organism-1
Human
基因ID-1
4793
SwissProt-1
Q15653
Organism-2
Mouse
SwissProt-2
Q60778
背景
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011],
细胞定位
Cytoplasm . Nucleus .





