Paxillin (phospho Tyr88) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611002
- 产品信息
商品描述
靶点-Target
Paxillin
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
68kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phospho-peptide around the phosphorylation site of human Paxillin (phospho Tyr88)
特异性
Phospho-Paxillin (Y88) Polyclonal Antibody detects endogenous levels of Paxillin protein only when phosphorylated at Y88.
基因名称
PXN
蛋白名称
Paxillin
别名
PXN;Paxillin
Organism-1
Human
基因ID-1
5829
SwissProt-1
P49023
Organism-2
Mouse
SwissProt-2
Q8VI36
背景
This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445). [provided by RefSeq, Aug 2011],
细胞定位
Cytoplasm, cytoskeleton . Cell junction, focal adhesion . Cytoplasm, cell cortex . Colocalizes with integrins at the cell periphery. Colocalize with PXN to membrane ruffles and the leading edge of migrating cells (PubMed:23128389). .





