MEK-6 (phospho Ser207) Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2610954

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商品描述
  • 靶点-Target

    MEK-6

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Calculated)

    37kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized phospho-peptide around the phosphorylation site of human MEK-6 (phospho Ser207)

  • 特异性

    Phospho-MEK-6 (S207) Polyclonal Antibody detects endogenous levels of MEK-6 protein only when phosphorylated at S207.

  • 基因名称

    MAP2K6

  • 蛋白名称

    Dual specificity mitogen-activated protein kinase kinase 6

  • 别名

    MAP2K6;MEK6;MKK6;PRKMK6;SKK3;Dual specificity mitogen-activated protein kinase kinase 6;MAP kinase kinase 6;MAPKK 6;MAPK/ERK kinase 6;MEK 6;Stress-activated protein kinase kinase 3;SAPK kinase 3;SAPKK-3;SAPKK3

  • Organism-1

    Human

  • 基因ID-1

    5608

  • SwissProt-1

    P52564

  • Organism-2

    Mouse

  • 基因ID-2

    26399

  • SwissProt-2

    P70236

  • 背景

    This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Binds to microtubules.