MEF-2D (phospho Ser444) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2610946
- 产品信息
商品描述
靶点-Target
MEF-2D
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
55kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MEF2D around the phosphorylation site of Ser444. AA range:410-459
特异性
Phospho-MEF-2D (S444) Polyclonal Antibody detects endogenous levels of MEF-2D protein only when phosphorylated at S444.
基因名称
MEF2D
蛋白名称
Myocyte-specific enhancer factor 2D
别名
MEF2D;Myocyte-specific enhancer factor 2D
Organism-1
Human
基因ID-1
4209
SwissProt-1
Q14814
Organism-2
Mouse
SwissProt-2
Q63943
Organism-3
Rat
基因ID-3
81518
SwissProt-3
O89038
背景
This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012],
细胞定位
Nucleus . Translocated by HDAC4 to nuclear dots.





