JAK1 (phospho Tyr1022) Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2610935

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商品描述
  • 靶点-Target

    JAK1

  • 反应性

    Human,Mouse,Rat

  • 应用

    IF,WB,IP,IHC,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    132kD

  • 推荐稀释比

    IF 1:50-200;WB 1:200-1:1000;IHC 1:100-1:300;ELISA 1:10000;Not yet tested in other applications;

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human JAK1 around the phosphorylation site of Tyr1022. AA range:988-1037

  • 特异性

    Phospho-JAK1 (Y1022) Polyclonal Antibody detects endogenous levels of JAK1 protein only when phosphorylated at Y1022.

  • 基因名称

    JAK1

  • 蛋白名称

    Tyrosine-protein kinase JAK1

  • 别名

    JAK1;JAK1A;JAK1B;Tyrosine-protein kinase JAK1;Janus kinase 1;JAK-1

  • Organism-1

    Human

  • 基因ID-1

    3716

  • SwissProt-1

    P23458

  • Organism-2

    Mouse

  • SwissProt-2

    P52332

  • 背景

    This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

  • 细胞定位

    Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated.