GSK3α/β (phospho Tyr279/216) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2610904
- 产品信息
商品描述
靶点-Target
GSK3α/β
反应性
Human,Mouse,Rat
应用
IF,WB,IHC,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
51,46kD
推荐稀释比
IF 1:50-200;WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;Not yet tested in other applications;
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GSK3 alpha/beta around the phosphorylation site of Tyr279/216. AA range:246-295
特异性
Phospho-GSK3α/β (Y279/216) Polyclonal Antibody detects endogenous levels of GSK3α/β protein only when phosphorylated at Y279/216.
基因名称
GSK3A/GSK3B
蛋白名称
Glycogen synthase kinase-3 alpha/beta
别名
GSK3A;Glycogen synthase kinase-3 alpha;GSK-3 alpha;Serine/threonine-protein kinase GSK3A;GSK3B;Glycogen synthase kinase-3 beta;GSK-3 beta;Serine/threonine-protein kinase GSK3B
Organism-1
Human
基因ID-1
2931
SwissProt-1
P49840;P49841
Organism-2
Mouse
基因ID-2
606496;56637
Organism-3
Rat
基因ID-3
50686;84027
SwissProt-3
P18265;P18266
背景
glycogen synthase kinase 3 alpha(GSK3A) Homo sapiens This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011],
细胞定位
apical dendrite;axon;beta-catenin destruction complex;cytoplasm;cytosol;mitochondrion;neuronal cell body;nucleus;postsynapse;proximal dendrite;





