Cdc25B (phospho Ser323) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2610839
- 产品信息
商品描述
靶点-Target
Cdc25B
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
70kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CDC25B around the phosphorylation site of Ser323. AA range:289-338
特异性
Phospho-Cdc25B (S323) Polyclonal Antibody detects endogenous levels of Cdc25B protein only when phosphorylated at S323.
基因名称
CDC25B
蛋白名称
M-phase inducer phosphatase 2
别名
CDC25B;CDC25HU2;M-phase inducer phosphatase 2;Dual specificity phosphatase Cdc25B
Organism-1
Human
基因ID-1
994
SwissProt-1
P30305
Organism-2
Mouse
基因ID-2
12531
SwissProt-2
P30306
Organism-3
Rat
基因ID-3
171103
SwissProt-3
P48966
背景
cell division cycle 25B(CDC25B) Homo sapiens CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole .





