Cdc25A (phospho Ser75) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2610837
- 产品信息
商品描述
靶点-Target
Cdc25A
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
59kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phospho-peptide around the phosphorylation site of human Cdc25A (phospho Ser75)
特异性
Phospho-Cdc25A (S75) Polyclonal Antibody detects endogenous levels of Cdc25A protein only when phosphorylated at S75.
基因名称
CDC25A
蛋白名称
M-phase inducer phosphatase 1
别名
CDC25A;M-phase inducer phosphatase 1;Dual specificity phosphatase Cdc25A
Organism-1
Human
基因ID-1
993
SwissProt-1
P30304
Organism-2
Mouse
SwissProt-2
P48964
Organism-3
Rat
基因ID-3
171102
SwissProt-3
P48965
背景
cell division cycle 25A(CDC25A) Homo sapiens CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
intracellular,nucleus,nucleoplasm,cytoplasm,cytosol,





