- 产品信息
商品描述
靶点-Target
HELB
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
120kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human HELB
特异性
This antibody detects endogenous levels of HELB at Human, Mouse
基因名称
HELB
蛋白名称
DNA helicase B (hDHB) (EC 3.6.4.12)
Organism-1
Human
基因ID-1
92797
SwissProt-1
Q8NG08
Organism-2
Mouse
基因ID-2
117599
SwissProt-2
Q6NVF4
细胞定位
Nucleus . Cytoplasm . Chromosome . Predominantly nuclear (PubMed:15146062). Phosphorylation at Ser-967 by CDK2 during the G1/S transition results in its nuclear export into the cytoplasm as cells approach and progress through S phase (PubMed:15146062). Following DNA damage, recruited to sites of double-strand breaks by the RPA complex (PubMed:26774285). Recruited to chromatin following DNA damage induced by UV irradiation, or camptothecin or hydroxyurea treatment (PubMed:22194613). .





