- 产品信息
商品描述
靶点-Target
SIRT7
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
44kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human SIRT7
特异性
This antibody detects endogenous levels of SIRT7 at Human, Mouse,Rat
基因名称
SIRT7 SIR2L7
蛋白名称
NAD-dependent protein deacetylase sirtuin-7 (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7)
Organism-1
Human
基因ID-1
51547
SwissProt-1
Q9NRC8
Organism-2
Mouse
基因ID-2
209011
SwissProt-2
Q8BKJ9
Organism-3
Rat
基因ID-3
303745
SwissProt-3
B2RZ55
细胞定位
Nucleus, nucleolus . Nucleus, nucleoplasm . Chromosome . Cytoplasm . Mainly localizes in the nucleolus and nucleoplasm (PubMed:24207024, PubMed:28886238, PubMed:28790157, PubMed:31075303). Associated with rDNA promoter and transcribed region (PubMed:16079181, PubMed:19174463). Associated with nucleolar organizer regions during mitosis (PubMed:16079181, PubMed:19174463). In response to stress, released from nucleolus to nucleoplasm (PubMed:24207024). Associated with chromatin (PubMed:22722849). In response to DNA damage, recruited to DNA double-strand breaks (DSBs) sites (PubMed:27436229) (Probable). Located close to the nuclear membrane when in the cytoplasm (PubMed:11953824). .





