- 产品信息
商品描述
靶点-Target
DST
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
833kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human DST
特异性
This antibody detects endogenous levels of DST at Human, Mouse
基因名称
DST BP230 BP240 BPAG1 DMH DT KIAA0728
蛋白名称
Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)
Organism-1
Human
基因ID-1
667
SwissProt-1
Q03001
Organism-2
Mouse
基因ID-2
13518
SwissProt-2
Q91ZU6
细胞定位
Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, stress fiber . Cell projection, axon . Associates with intermediate filaments, actin and microtubule cytoskeletons. Localizes to actin stress fibers and to actin-rich ruffling at the cortex of cells (By similarity). Associated at the growing distal tip of microtubules. .; [Isoform 1]: Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, myofibril, sarcomere, H zone . Localizes to microtubules and actin microfilaments throughout the cytoplasm and at focal contact attachments at the plasma membrane. .; [Isoform 2]: Cytoplasm, cytoskeleton . Colocalizes both cortical and cytoplasmic actin filaments. .; [Isoform 3]: Cytoplasm, cytoskeleton. Cell junction, hemidesmosome. Localizes to actin and intermediate filaments cytoskeletons (By similarity). Colocalizes with the epidermal KRT5-KRT14 intermediate filaments network of keratins. Colocalizes with ITGB4 at the leading edge of migrating keratinocytes. .; [Isoform 6]: Nucleus . Nucleus envelope . Membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, stress fiber . Localizes to actin and intermediate filaments cytoskeletons. Localizes to central actin stress fibers around the nucleus and is excluded form focal contact sites in myoblast cells. Translocates to the nucleus (By similarity). Associates with actin cytoskeleton in sensory neurons. .; [Isoform 7]: Cytoplasm, cytoskeleton . Cell projection, axon . Membrane . Associates with axonal microtubules and intermediate filaments, but not with actin cytoskeleton, in sensory neurons.; [Isoform 8]: Cytoplasm, cytoskeleton . Cytoplasm, cell cortex . Cell membrane ; Lipid-anchor .





