FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PKD1
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
473kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 4100-4150
特异性
This antibody detects endogenous levels of Polycystin 1 at Human, Mouse
基因名称
PKD1
蛋白名称
Polycystin-1 (Autosomal dominant polycystic kidney disease 1 protein)
Organism-1
Human
基因ID-1
5310
SwissProt-1
P98161
Organism-2
Mouse
基因ID-2
18763
SwissProt-2
O08852
细胞定位
Cell membrane ; Multi-pass membrane protein . Cell projection, cilium . Endoplasmic reticulum . Golgi apparatus . PKD1 localization to the plasma and ciliary membranes requires PKD2, is independent of PKD2 channel activity, and involves stimulation of PKD1 autoproteolytic cleavage at the GPS domain. PKD1:PKD2 interaction is required to reach the Golgi apparatus from endoplasmic reticulum and then traffic to the cilia (By similarity). Ciliary localization of PKD1 requires BBS1 and ARL6/BBS3 (By similarity). Cell surface localization requires GANAB (PubMed:27259053). .
