FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TREX1
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
35kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human TREX1
特异性
This antibody detects endogenous levels of TREX1 at Human, Mouse
基因名称
TREX1
蛋白名称
Three prime repair exonuclease 1 (3'-5' exonuclease TREX1) (DNase III)
Organism-1
Human
基因ID-1
11277
SwissProt-1
Q9NSU2
Organism-2
Mouse
基因ID-2
22040
SwissProt-2
Q91XB0
细胞定位
Nucleus . Cytoplasm, cytosol . Endoplasmic reticulum membrane ; Peripheral membrane protein . Retained in the cytoplasm through the C-terminal region (By similarity). Localization to the endoplasmic reticulum membrane is required to direct TREX1 to ruptured micronuclei (PubMed:33476576). In response to DNA damage, translocates to the nucleus where it is specifically recruited to replication foci (PubMed:16818237). Translocation to the nucleus also occurs during GZMA-mediated cell death (PubMed:16818237). .
