- 产品信息
商品描述
靶点-Target
SERINC5
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
47kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human SERINC5
特异性
This antibody detects endogenous levels of SERINC5 at Human, Mouse,Rat
基因名称
SERINC5 C5orf12
蛋白名称
Serine incorporator 5
Organism-1
Human
基因ID-1
256987
SwissProt-1
Q86VE9
Organism-2
Mouse
基因ID-2
218442
SwissProt-2
Q8BHJ6
Organism-3
Rat
基因ID-3
170907
SwissProt-3
Q63175
细胞定位
Cell membrane ; Multi-pass membrane protein .; Cytoplasm, perinuclear region . (Microbial infection) Upon HIV-1 infection, it is redirected to perinuclear region following interaction with HIV-1 Nef, excluding it from virions particles, thereby preventing subsequent antiviral defense activity (PubMed:26416733, PubMed:26416734). Localizes to the cell membrane, where it is efficiently incorporated into budding virions and impairs subsequent virion entry into target cells (PubMed:26416733, PubMed:26416734). .





