- 产品信息
商品描述
靶点-Target
LPXN
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
42kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human LPXN
特异性
This antibody detects endogenous levels of LPXN at Human, Mouse
基因名称
LPXN LDLP
蛋白名称
Leupaxin
Organism-1
Human
基因ID-1
9404
SwissProt-1
O60711
Organism-2
Mouse
基因ID-2
107321
SwissProt-2
Q99N69
细胞定位
Cytoplasm. Cell junction, focal adhesion. Nucleus. Cytoplasm, perinuclear region . Cell projection, podosome. Cell membrane. Shuttles between the cytoplasm and nucleus. Recruited to the cell membrane following B-cell antigen receptor (BCR) cross-linking in B-cells. Enhanced focal adhesion kinase activity (PTK2/FAK) attenuates its nuclear accumulation and limits its ability to enhance serum response factor (SRF)-dependent gene transcription. Targeting to focal adhesions is essential for its tyrosine phosphorylation in response to bombesin.





