FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SYNPO2
反应性
Human
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
120kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Myopodin
特异性
This antibody detects endogenous levels of Myopodin at Human
基因名称
SYNPO2
蛋白名称
Synaptopodin-2 (Genethonin-2) (Myopodin)
Organism-1
Human
基因ID-1
171024
SwissProt-1
Q9UMS6
Organism-2
Mouse
SwissProt-2
Q91YE8
细胞定位
Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, Z line . Cell junction, focal adhesion . Shuttles between the nucleus and the cytoplasm in a differentiation-dependent and stress-induced fashion. In undifferentiated myoblasts strongly expressed in the nucleus, after induction of myotube differentiation is located to both nucleus and cytoplasm along acting filaments, and in differentiated myotubes is located at the Z lines. Upon stress redistributes from cytoplasm of myoblasts and myotubes to the nucleus. Nuclear import is KPNA2-dependent and promoted by phosphorylation by PKA and/or CaMK2, and inhibition of calcineurin. The nuclear export is XPO1-dependent (By similarity). Localized in a fiber-like pattern, partly overlapping with filamentous actin (PubMed:18371299). .; [Isoform 1]: Cytoplasm, cytoskeleton . Localizes to induced actin bundles with contiguous staining. .; [Isoform 2]: Cytoplasm, cytoskeleton . Localizes to induced actin bundles with punctuate staining. .; [Isoform 3]: Cytoplasm, cytoskeleton . Localizes to induced irregular actin bundles with contiguous and punctuated staining. .; [Isoform 4]: Cytoplasm, cytoskeleton . Localizes to induced actin bundles with punctuate staining. .; [Isoform 5]: Cytoplasm, cytoskeleton . Localizes to induced actin bundles with contiguous staining. .
