FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GBF1
反应性
Human
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
204kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human GBF1
特异性
This antibody detects endogenous levels of GBF1 at Human
基因名称
GBF1 KIAA0248
蛋白名称
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1)
Organism-1
Human
基因ID-1
8729
SwissProt-1
Q92538
细胞定位
Golgi apparatus, cis-Golgi network . Endoplasmic reticulum-Golgi intermediate compartment . Golgi apparatus, trans-Golgi network . Golgi apparatus . Cytoplasm . Lipid droplet . Membrane; Peripheral membrane protein . Cycles rapidly on and off early Golgi membranes (PubMed:15616190). Stabilized on membranes when complexed with ARF1-GDP and is released from both ARF1 and membranes after it catalyzes GDP displacement and ARF1 binds GTP. Continuous cycles of recruitment and dissociation of GBF1 to membranes are required for sustained ARF activation and COP I recruitment (PubMed:15813748). In neutrophils is translocated from the Golgi to the leading edge upon GPCR stimulation (PubMed:22573891). Localization to lipid droplets is questionable (PubMed:22185782). .
