DTX3L rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2608611

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商品描述
  • 靶点-Target

    DTX3L

  • 反应性

    Human,Mouse

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    81kD

  • 推荐稀释比

    WB 1:500-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human DTX3L

  • 特异性

    This antibody detects endogenous levels of DTX3L at Human, Mouse

  • 基因名称

    DTX3L BBAP

  • 蛋白名称

    E3 ubiquitin-protein ligase DTX3L (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2)

  • Organism-1

    Human

  • 基因ID-1

    151636

  • SwissProt-1

    Q8TDB6

  • Organism-2

    Mouse

  • 基因ID-2

    209200

  • SwissProt-2

    Q3UIR3

  • 细胞定位

    Cytoplasm . Nucleus . Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Lysosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Translocates to the nucleus in response to IFNG or IFNB1 stimulation (PubMed:26479788). Localizes at sites of DNA damage in a PARP1-dependent manner (PubMed:23230272). Localization to early endosomes is increased upon CXCL12 stimulation where it co-localizes with ITCH, CXCL4, HGS and STAM (PubMed:24790097). A minor proportion localizes to lysosomes (PubMed:24790097). .