FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
WDFY3
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
388kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human WDFY3
特异性
This antibody detects endogenous levels of WDFY3 at Human, Mouse
基因名称
WDFY3 KIAA0993
蛋白名称
WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy)
Organism-1
Human
基因ID-1
23001
SwissProt-1
Q8IZQ1
Organism-2
Mouse
基因ID-2
72145
SwissProt-2
Q6VNB8
细胞定位
Nucleus membrane . Cytoplasm, cytosol . Nucleus, PML body . Membrane; Peripheral membrane protein ; Cytoplasmic side . Perikaryon . Cell projection, axon . Relocalization from the nucleus to the cytosol is stimulated by cellular stress, such as starvation or proteasomal inhibition. In the cytosol of starved cells, colocalizes with autophagic structures (PubMed:15292400, PubMed:20168092, PubMed:20971078, PubMed:20417604). This redistribution is dependent on p62/SQSTM1 (PubMed:20168092). When nuclear export is blocked by treatment with leptomycin B, accumulates in nuclear bodies, that completely or partially colocalize with promyelocytic leukemia (PML) bodies (PubMed:20168092). Localizes throughout neurons, including within axons. In neurons, enriched in the light membrane fraction along with the synaptosomal membrane protein synaptophysin and the membrane-bound form of LC3/MAP1LC3A/MAP1LC3B, called LC3-II, a classic marker for autophagic vesicles (By similarity). .
