IA-2/PTPRN rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2608443

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商品描述
  • 靶点-Target

    PTPRN

  • 反应性

    Human,Rat

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    108kD

  • 推荐稀释比

    WB 1:500-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human IA-2/PTPRN

  • 特异性

    This antibody detects endogenous levels of IA-2/PTPRN at Human,Rat

  • 基因名称

    PTPRN ICA3 ICA512

  • 蛋白名称

    Receptor-type tyrosine-protein phosphatase-like N (R-PTP-N) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3) (PTP IA-2)

  • Organism-1

    Human

  • 基因ID-1

    5798

  • SwissProt-1

    Q16849

  • Organism-2

    Mouse

  • SwissProt-2

    Q60673

  • Organism-3

    Rat

  • 基因ID-3

    116660

  • SwissProt-3

    Q63259

  • 细胞定位

    Membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass type I membrane protein . Perikaryon . Cell projection, axon . Cell junction, synapse . Cell membrane ; Single-pass type I membrane protein . Endosome . Detected on neuronal secretory vesicles, but not on synaptic vesicles. Colocalizes with insulin-containing secretory granules (PubMed:25561468). Primarily detected on secretory vesicle membranes. Transiently found at the cell membrane, when secretory vesicles fuse with the cell membrane to release their cargo. Is then endocytosed and recycled to secretory vesicles via the Golgi apparatus membranes. .; [ICA512-transmembrane fragment]: Cytoplasmic vesicle, secretory vesicle membrane .; [ICA512-cleaved cytosolic fragment]: Nucleus .