- 产品信息
商品描述
靶点-Target
PTPRN
反应性
Human,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
108kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human IA-2/PTPRN
特异性
This antibody detects endogenous levels of IA-2/PTPRN at Human,Rat
基因名称
PTPRN ICA3 ICA512
蛋白名称
Receptor-type tyrosine-protein phosphatase-like N (R-PTP-N) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3) (PTP IA-2)
Organism-1
Human
基因ID-1
5798
SwissProt-1
Q16849
Organism-2
Mouse
SwissProt-2
Q60673
Organism-3
Rat
基因ID-3
116660
SwissProt-3
Q63259
细胞定位
Membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass type I membrane protein . Perikaryon . Cell projection, axon . Cell junction, synapse . Cell membrane ; Single-pass type I membrane protein . Endosome . Detected on neuronal secretory vesicles, but not on synaptic vesicles. Colocalizes with insulin-containing secretory granules (PubMed:25561468). Primarily detected on secretory vesicle membranes. Transiently found at the cell membrane, when secretory vesicles fuse with the cell membrane to release their cargo. Is then endocytosed and recycled to secretory vesicles via the Golgi apparatus membranes. .; [ICA512-transmembrane fragment]: Cytoplasmic vesicle, secretory vesicle membrane .; [ICA512-cleaved cytosolic fragment]: Nucleus .





