- 产品信息
商品描述
靶点-Target
ERCC6L
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
138kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human ERCC6L
特异性
This antibody detects endogenous levels of ERCC6L at Human, Mouse
基因名称
ERCC6L PICH
蛋白名称
DNA excision repair protein ERCC-6-like (ATP-dependent helicase ERCC6-like) (PLK1-interacting checkpoint helicase) (Tumor antigen BJ-HCC-15)
Organism-1
Human
基因ID-1
54821
SwissProt-1
Q2NKX8
Organism-2
Mouse
基因ID-2
236930
SwissProt-2
Q8BHK9
细胞定位
Chromosome, centromere . Chromosome, centromere, kinetochore . Chromosome . Localizes to kinetochores, inner centromeres and thin threads connecting separating chromosomes even during anaphase. In prometaphase cells, it mostly concentrates in between kinetochores. In metaphase, it localizes to numerous thin threads that stretch between sister kinetochores of the aligned chromosomes and are composed of catenated centromeric DNA. Evolution from inner centromeres to thin threads takes place in response to tension. Resolution of thin threads requires topoisomerase 2-alpha (TOP2A) after anaphase onset. .





