FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CRACR2A
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
80kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human CRACR2A
特异性
This antibody detects endogenous levels of CRACR2A at Human, Mouse
基因名称
EFCAB4B CRACR2A
蛋白名称
EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A)
Organism-1
Human
基因ID-1
84766
SwissProt-1
Q9BSW2
Organism-2
Mouse
基因ID-2
381812
SwissProt-2
Q3UP38
细胞定位
[Isoform 1]: Cytoplasm .; [Isoform 2]: Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center . Cell membrane . Golgi apparatus membrane . Golgi apparatus, trans-Golgi network membrane . Vesicle . T-cell activation-induced elevation of intracellular of Ca(2+) stimulates its transport toward the microtubule organizing center (MTOC) (PubMed:30814157). Histamine stimulation induces a trafficking to the MTOC in a GTP-binding-dependent but Ca(2+)-binding-independent manner (PubMed:31092558). Localizes to Golgi membrane in resting T-cells and upon its interaction with VAV1, is translocated from the Golgi membrane to the immunological synapse via subsynaptic vesicles (PubMed:27016526). Its localization in the Golgi membrane requires isoprenylation and GTP-binding (PubMed:27016526). .
