FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MR1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
38kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human MR1
特异性
This antibody detects endogenous levels of MR1 at Human, Mouse,Rat
基因名称
MR1
蛋白名称
Major histocompatibility complex class I-related gene protein (MHC class I-related gene protein) (Class I histocompatibility antigen-like protein)
Organism-1
Human
基因ID-1
3140
SwissProt-1
Q95460
Organism-2
Mouse
基因ID-2
15064
SwissProt-2
Q8HWB0
Organism-3
Rat
基因ID-3
25119
SwissProt-3
O19477
细胞定位
Cell membrane ; Single-pass type I membrane protein. Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Golgi apparatus membrane ; Single-pass type I membrane protein . Early endosome membrane ; Single-pass type I membrane protein . Late endosome membrane ; Single-pass type I membrane protein . In the absence of antigen remains within the endoplasmic reticulum where it acts as a metabolite sensor. Antigen binding triggers trafficking of the ternary complex to the plasma membrane. After presentation, most of these complexes are rapidly internalized and degraded via endocytosis. A small subset recycles via endosomes back to the plasma membrane and may thus acquire and present new antigens that do not efficiently reach the endoplasmic reticulum. .; [Isoform 1]: Cell membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein .; [Isoform 3]: Cell membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein . The larger proportion remains in the ER in an immature state. The subset that reach cell surface does it through a B2M-independent pathway. .; [Isoform 4]: Secreted .
