- 产品信息
商品描述
靶点-Target
DHX36
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
111kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human DHX36
特异性
This antibody detects endogenous levels of DHX36 at Human, Mouse
基因名称
DHX36 DDX36 KIAA1488 MLEL1 RHAU
蛋白名称
Probable ATP-dependent RNA helicase DHX36 (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE)
Organism-1
Human
基因ID-1
170506
SwissProt-1
Q9H2U1
Organism-2
Mouse
基因ID-2
72162
SwissProt-2
Q8VHK9
细胞定位
Nucleus . Cytoplasm . Cytoplasm, cytosol . Cytoplasm, Stress granule . Nucleus speckle . Chromosome, telomere . Mitochondrion . Perikaryon . Cell projection, dendrite . Cell projection, axon . Predominantly localized in the nucleus (PubMed:18279852). Colocalizes with SRSF2 in nuclear speckles (PubMed:18279852). Colocalizes with DDX5 in nucleolar caps upon transcription inhibition (PubMed:18279852). Accumulates and colocalized with TIA1 in cytoplasmic stress granules (SGs) in an arsenite-, heat shock- and RNA-binding-dependent manner (PubMed:18854321). Shuttles into and out of SGs in an ATPase-dependent manner (PubMed:18854321). Colocalizes in the cytosol with the multi-helicase-TICAM1 complex that translocates to the mitochondria upon poly(I:C) RNA ligand stimulation (By similarity). .; [Isoform 1]: Nucleus . Cytoplasm . Preferentially localized in the nucleus (PubMed:14731398). Excluded from nucleoli (PubMed:14731398). .; [Isoform 2]: Nucleus . Cytoplasm . Preferentially localized in the cytoplasm (PubMed:14731398). Excluded from nucleoli (PubMed:14731398). .





