FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
RNF8
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
53kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human RNF8
特异性
This antibody detects endogenous levels of RNF8 at Human, Mouse,Rat
基因名称
RNF8 KIAA0646
蛋白名称
E3 ubiquitin-protein ligase RNF8 (hRNF8) (RING finger protein 8)
Organism-1
Human
基因ID-1
9025
SwissProt-1
O76064
Organism-2
Mouse
基因ID-2
58230
SwissProt-2
Q8VC56
Organism-3
Rat
基因ID-3
361815
SwissProt-3
Q4KLN8
细胞定位
Nucleus . Cytoplasm . Midbody . Chromosome, telomere . Recruited at uncapped telomeres (By similarity). Following DNA damage, such as double-strand breaks, recruited to the sites of damage (PubMed:18001824, PubMed:18077395, PubMed:22266820, PubMed:23233665). During prophase, concomitant with nuclear envelope breakdown, localizes throughout the cell, with a dotted pattern. In telophase, again in the nucleus and also with a discrete dotted pattern in the cytoplasm. In late telophase and during cytokinesis, localizes in the midbody of the tubulin bridge joining the daughter cells. Does not seem to be associated with condensed chromosomes at any time during the cell cycle. During spermatogenesis, sequestered in the cytoplasm by PIWIL1: RNF8 is released following ubiquitination and degradation of PIWIL1. .
