- 产品信息
商品描述
靶点-Target
ACTN4
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
100kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human ACTN4
特异性
This antibody detects endogenous levels of ACTN4 at Human, Mouse,Rat
基因名称
ACTN4
蛋白名称
Alpha-actinin-4 (F-actin cross-linking protein) (Non-muscle alpha-actinin 4)
Organism-1
Human
基因ID-1
81
SwissProt-1
O43707
Organism-2
Mouse
基因ID-2
60595
SwissProt-2
P57780
Organism-3
Rat
基因ID-3
63836
SwissProt-3
Q9QXQ0
细胞定位
Nucleus . Cytoplasm . Cell junction . Cytoplasm, cytoskeleton, stress fiber . Cytoplasm, perinuclear region . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Expressed in the perinuclear rim and manchette structure in early elongating spermatids during spermiogenesis (By similarity). Nuclear translocation can be induced by the PI3 kinase inhibitor wortmannin or by cytochalasin D. Exclusively localized in the nucleus in a limited number of cell lines (breast cancer cell line MCF-7, oral floor cancer IMC-2, and bladder cancer KU-7). .





