FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
STIP1/HOP
反应性
Human,Mouse,Rat
应用
IHC,WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
64kD
推荐稀释比
IHC1:50-200;WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human STIP1/HOP AA range: 250-300
特异性
This antibody detects endogenous levels of STIP1/HOP at Human, Mouse,Rat
基因名称
STIP1
蛋白名称
STIP1/HOP
别名
Stress-induced-phosphoprotein 1;STI1;Hsc70/Hsp90-organizing protein;Hop;Renal carcinoma antigen NY-REN-11;Transformation-sensitive protein IEF SSP 3521;
Organism-1
Human
基因ID-1
10963
SwissProt-1
P31948
Organism-2
Mouse
基因ID-2
20867
SwissProt-2
Q60864
Organism-3
Rat
基因ID-3
192277
SwissProt-3
O35814
背景
STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009],
细胞定位
Cytoplasm . Nucleus . Dynein axonemal particle .
