FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ATG13
反应性
Human,Mouse,Rat
应用
IHC,WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
72kD
推荐稀释比
IHC1:50-200;WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human ATG13 AA range: 182-232
特异性
This antibody detects endogenous levels of ATG13 at Human, Mouse,Rat
基因名称
ATG13 KIAA0652
蛋白名称
ATG13
别名
Autophagy-related protein 13
Organism-1
Human
基因ID-1
9776
SwissProt-1
O75143
Organism-2
Mouse
基因ID-2
51897
SwissProt-2
Q91YI1
背景
Atg13 was identified as a constitutively expressed protein that was genetically linked to Atg1/Apg1, a protein kinase required for autophagy. Overexpression of Atg1 suppresses the defects in autophagy observed in Atg13 mutants. Autophagy requires a direct association between Atg1 and Atg13, and is inhibited by TOR-dependent phosphorylation of Atg13 under high-nutrient conditions.
细胞定位
Cytoplasm, cytosol . Preautophagosomal structure . Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. .
