FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ACE2
反应性
Human,Mouse,Rat
应用
IHC,WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
120-135kD
推荐稀释比
IHC1:50-200;WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human ACE2 AA range: 425-475
特异性
This antibody detects endogenous levels of ACE2 at Human, Mouse,Rat
基因名称
ACE2 UNQ868/PRO1885
蛋白名称
ACE2
别名
Angiotensin-converting enzyme 2;ACE-related carboxypeptidase;Angiotensin-converting enzyme homolog;ACEH;Metalloprotease MPROT15;[Cleaved into: Processed angiotensin-converting enzyme 2]
Organism-1
Human
基因ID-1
59272
SwissProt-1
Q9BYF1
Organism-2
Mouse
基因ID-2
70008
SwissProt-2
Q8R0I0
Organism-3
Rat
基因ID-3
302668
SwissProt-3
Q5EGZ1
背景
angiotensin I converting enzyme 2(ACE2) Homo sapiens The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
细胞定位
[Processed angiotensin-converting enzyme 2]: Secreted .; Cell membrane ; Single-pass type I membrane protein . Cytoplasm . Cell projection, cilium . Apical cell membrane . Detected in both cell membrane and cytoplasm in neurons. .; [Isoform 2]: Apical cell membrane .
