- 产品信息
商品描述
靶点-Target
PDK4
反应性
Human,Mouse,Rat
应用
IHC,WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
46kD
推荐稀释比
IHC1:50-200;WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human PDK4 AA range: 34-84
特异性
This antibody detects endogenous levels of PDK4 at Human, Mouse,Rat
基因名称
PDK4 PDHK4
蛋白名称
PDK4
别名
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial;Pyruvate dehydrogenase kinase isoform 4;
Organism-1
Human
基因ID-1
5166
SwissProt-1
Q16654
Organism-2
Mouse
基因ID-2
27273
SwissProt-2
O70571
Organism-3
Rat
基因ID-3
89813
SwissProt-3
O54937
背景
Pyruvate dehydrogenase kinase isoform4 (PDK4) is also named as PDHK4 and belongs to the PDK/BCKDK protein kinase family. It is upregulated by starvation in many tissues of the body during starvation. This causes inactivation of the pyruvate dehydrogenase complex which blocks pyruvate oxidation and conserves lactate and alanine for gluconeogenesis.
细胞定位
Mitochondrion matrix.





