Bmi-1 Rabbit Polyclonal Antibody(F270)
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2607653
- 产品信息
商品描述
靶点-Target
Bmi-1
反应性
Human
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
37-43kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
克隆号
F270
免疫原
Recombinant Protein derived from human Bmi-1
特异性
This antibody detects endogenous levels of human Bmi-1
基因名称
BMI1 PCGF4 RNF51
蛋白名称
Bmi-1
别名
Polycomb complex protein BMI-1;Polycomb group RING finger protein 4;RING finger protein 51;
Organism-1
Human
基因ID-1
100532731
SwissProt-1
P35226
背景
BMI1 proto-oncogene, polycomb ring finger(BMI1) Homo sapiens This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015],
细胞定位
Nucleus . Cytoplasm .





