Bmi-1 Rabbit Polyclonal Antibody(F270)

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2607653

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商品描述
  • 靶点-Target

    Bmi-1

  • 反应性

    Human

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    37-43kD

  • 推荐稀释比

    WB 1:500-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 克隆号

    F270

  • 免疫原

    Recombinant Protein derived from human Bmi-1

  • 特异性

    This antibody detects endogenous levels of human Bmi-1

  • 基因名称

    BMI1 PCGF4 RNF51

  • 蛋白名称

    Bmi-1

  • 别名

    Polycomb complex protein BMI-1;Polycomb group RING finger protein 4;RING finger protein 51;

  • Organism-1

    Human

  • 基因ID-1

    100532731

  • SwissProt-1

    P35226

  • 背景

    BMI1 proto-oncogene, polycomb ring finger(BMI1) Homo sapiens This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015],

  • 细胞定位

    Nucleus . Cytoplasm .