FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CABP
反应性
Rat,Mouse
应用
WB,IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
40kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic Peptide of CABP
特异性
The antibody detects endogenous CABP protein
基因名称
CABP1
蛋白名称
Calcium-binding protein 1 (CaBP1) (Calbrain) (Caldendrin)
别名
Calcium-binding protein 1;CaBP1;Calbrain;Caldendrin;
Organism-1
Human
基因ID-1
9478
SwissProt-1
Q9NZU7
Organism-2
Mouse
SwissProt-2
Q9JLK7
Organism-3
Rat
SwissProt-3
O88751
背景
Calcium binding proteins are an important component of calcium mediated cellular signal transduction. This gene encodes a protein that belongs to a subfamily of calcium binding proteins which share similarity to calmodulin. The protein encoded by this gene regulates the gating of voltage-gated calcium ion channels. This protein inhibits calcium-dependent inactivation and supports calcium-dependent facilitation of ion channels containing voltage-dependent L-type calcium channel subunit alpha-1C. This protein also regulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors, P/Q-type voltage-gated calcium channels, and transient receptor potential channel TRPC5. This gene is predominantly expressed in retina and brain. Alternative splicing results in multiple transcript variants encoding disinct isoforms. [provided by RefSeq, Jul 2012],
细胞定位
Cytoplasm, cytoskeleton . Cytoplasm, perinuclear region . Cell membrane ; Lipid-anchor; Cytoplasmic side. Golgi apparatus . Cell junction, synapse, postsynaptic density . L-CaBP1 is associated most likely with the cytoskeletal structures, whereas S-CaBP1 is localized at or near the plasma membrane. .; [Isoform L-CaBP1]: Cytoplasm, cytoskeleton . L-CaBP1 is associated most likely with the cytoskeletal structures. .; [Isoform S-CaBP1]: Cytoplasm, cell cortex. Cell membrane ; Lipid-anchor . S-CaBP1 is localized at or near the plasma membrane.
