- 产品信息
商品描述
靶点-Target
Cav1.3
反应性
Human,Rat,Mouse
应用
IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
245kD
推荐稀释比
IHC 1:100-200;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic Peptide of Cav1.3 AA range: 1060-1140
特异性
Cav1.3 protein(A202) detects endogenous levels of Cav1.3
基因名称
CACNA1D
蛋白名称
Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (Voltage-gated calcium channel subunit alpha Cav1.3)
别名
Voltage-dependent L-type calcium channel subunit alpha-1D;Calcium channel, L type, alpha-1 polypeptide, isoform 2;Voltage-gated calcium channel subunit alpha Cav1.3;
Organism-1
Human
基因ID-1
776
SwissProt-1
Q01668
Organism-2
Mouse
SwissProt-2
Q99246
Organism-3
Rat
SwissProt-3
P27732
背景
calcium voltage-gated channel subunit alpha1 D(CACNA1D) Homo sapiens Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],
细胞定位
Membrane ; Multi-pass membrane protein .





