Cav3.2 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2607640

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商品描述
  • 靶点-Target

    Cav3.2

  • 反应性

    Human,Rat,Mouse

  • 应用

    IHC,IF

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    260kD

  • 推荐稀释比

    IHC 1:50-100;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthetic Peptide of Cav3.2 AA range: 1718-1768

  • 特异性

    Cav3.2 protein(A208) detects endogenous levels of Cav3.2

  • 基因名称

    CACNA1H

  • 蛋白名称

    Voltage-dependent T-type calcium channel subunit alpha-1H (Low-voltage-activated calcium channel alpha1 3.2 subunit) (Voltage-gated calcium channel subunit alpha Cav3.2)

  • 别名

    CACNA1H;Voltage-dependent T-type calcium channel subunit alpha-1H;Low-voltage-activated calcium channel alpha1 3.2 subunit;Voltage-gated calcium channel subunit alpha Cav3.2

  • Organism-1

    Human

  • 基因ID-1

    8912

  • SwissProt-1

    O95180

  • Organism-2

    Mouse

  • SwissProt-2

    O88427

  • Organism-3

    Rat

  • SwissProt-3

    Q9EQ60

  • 背景

    calcium voltage-gated channel subunit alpha1 H(CACNA1H) Homo sapiens This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cell membrane ; Multi-pass membrane protein . Interaction with STAC increases expression at the cell membrane. .