- 产品信息
商品描述
靶点-Target
CLIC1
反应性
Human,Rat,Mouse
应用
IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
30kD
推荐稀释比
IHC 1:100-200;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic Peptide of CLIC1 AA range: 166-216
特异性
CLIC1 protein(A216) detects endogenous levels of CLIC1
基因名称
CLIC1
蛋白名称
Chloride intracellular channel protein 1 (Chloride channel ABP) (Nuclear chloride ion channel 27) (NCC27) (Regulatory nuclear chloride ion channel protein) (hRNCC)
别名
Chloride intracellular channel protein 1;Chloride channel ABP;Nuclear chloride ion channel 27;NCC27;Regulatory nuclear chloride ion channel protein;hRNCC;
Organism-1
Human
基因ID-1
1192
SwissProt-1
O00299
Organism-2
Mouse
SwissProt-2
Q9Z1Q5
Organism-3
Rat
SwissProt-3
Q6MG61
背景
chloride intracellular channel 1(CLIC1) Homo sapiens Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Nucleus membrane ; Single-pass membrane protein . Cytoplasm . Cell membrane ; Single-pass membrane protein . Mostly in the nucleus including in the nuclear membrane (PubMed:9139710, PubMed:12681486). Small amount in the cytoplasm and the plasma membrane (PubMed:9139710). Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (PubMed:11940526, PubMed:11551966, PubMed:14613939). .





