- 产品信息
商品描述
靶点-Target
CNTF
反应性
Human,Rat,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
30kD
推荐稀释比
WB 1:500-1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic Peptide of CNTF
特异性
CNTF protein(A218) detects endogenous levels of CNTF
基因名称
CNTF
蛋白名称
Ciliary neurotrophic factor (CNTF)
别名
CNTF;Ciliary neurotrophic factor;CNTF
Organism-1
Human
基因ID-1
1270
SwissProt-1
P26441
Organism-2
Mouse
SwissProt-2
P51642
Organism-3
Rat
SwissProt-3
P20294
背景
The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010],
细胞定位
Cytoplasm.





