FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
COX1
反应性
Human
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70kD
推荐稀释比
WB 1:1000
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Polyclonal
免疫原
Synthetic Peptide of COX1 AA range: 483-533
特异性
The antibody detects endogenous COX1 proteins.
基因名称
PTGS1
蛋白名称
Prostaglandin G/H synthase 1
别名
PTGS1;COX1;Prostaglandin G/H synthase 1;Cyclooxygenase-1;COX-1;Prostaglandin H2 synthase 1;PGH synthase 1;PGHS-1;PHS 1;Prostaglandin-endoperoxide synthase 1
Organism-1
Human
基因ID-1
5742
SwissProt-1
P23219
Organism-2
Mouse
基因ID-2
19224
SwissProt-2
P22437
Organism-3
Rat
基因ID-3
24693
SwissProt-3
Q63921
背景
This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
细胞定位
Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
