FGF-2 Polyclonal Antibody
¥680.00
Endothelin B Receptor Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2607623
- 产品信息
商品描述
靶点-Target
Endothelin B Receptor
反应性
Human,Rat,Mouse
应用
IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
50kD
推荐稀释比
IHC 1:100-200;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic Peptide of Endothelin B Receptor AA range: 270-350
特异性
Endothelin B Receptor protein(A221) detects endogenous levels of Endothelin B Receptor
基因名称
EDNRB
蛋白名称
Endothelin B receptor (ET-B) (ET-BR) (Endothelin receptor non-selective type)
别名
Endothelin B receptor;ET-B;ET-BR;Endothelin receptor non-selective type;
Organism-1
Human
基因ID-1
1910
SwissProt-1
P24530
Organism-2
Mouse
SwissProt-2
P48302
Organism-3
Rat
SwissProt-3
P21451
背景
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016],
细胞定位
Cell membrane ; Multi-pass membrane protein. internalized after activation by endothelins. .
