FGF-2 Polyclonal Antibody
¥680.00
GABA A Receptor α4 Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2607614
- 产品信息
商品描述
靶点-Target
GABA A Receptor α4
反应性
Human,Rat,Mouse
应用
WB,IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
62kD
推荐稀释比
WB 1:1000-2000;IHC 1:100-200;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic Peptide of GABA A Receptor α4 AA range: 149-199
特异性
GABA A Receptor α4 protein(A226) detects endogenous levels of GABA A Receptor α4
基因名称
GABRA4
蛋白名称
Gamma-aminobutyric acid receptor subunit alpha-4 (GABA(A) receptor subunit alpha-4)
别名
GABRA4;Gamma-aminobutyric acid receptor subunit alpha-4;GABA;A;receptor subunit alpha-4
Organism-1
Human
基因ID-1
2557
SwissProt-1
P48169
Organism-2
Mouse
SwissProt-2
Q9D6F4
Organism-3
Rat
SwissProt-3
P28471
背景
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011],
细胞定位
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
