FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GAPDH
反应性
Human,Mouse,Rat,Rabbit,Ch,Mk,sheep,X,Fish,Chicken,Guinea Pig,Duck
应用
WB,IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
37kD
推荐稀释比
WB 1:5000;IHC 1:200;IF 1:50-200
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Polyclonal
免疫原
Recombinant Protein of GAPDH
特异性
The antibody detects endogenous GAPDH protein.
基因名称
GAPDH
蛋白名称
Glyceraldehyde-3-phosphate dehydrogenase
别名
GAPDH;GAPD;CDABP0047;OK/SW-cl.12;Glyceraldehyde-3-phosphate dehydrogenase;GAPDH;Peptidyl-cysteine S-nitrosylase GAPDH
Organism-1
Human
基因ID-1
2597
SwissProt-1
P04406
Organism-2
Mouse
基因ID-2
100042025
SwissProt-2
P16858
Organism-3
Rat
基因ID-3
24383
SwissProt-3
P04797
背景
glyceraldehyde-3-phosphate dehydrogenase(GAPDH) Homo sapiens This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferri
细胞定位
Cytoplasm, cytosol . Nucleus . Cytoplasm, perinuclear region . Membrane . Cytoplasm, cytoskeleton . Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal (By similarity). Postnuclear and Perinuclear regions (PubMed:12829261). .
