GRIK2 (GluR6) Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2607601

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商品描述
  • 靶点-Target

    GRIK2

  • 反应性

    Human

  • 应用

    IHC,IF

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    103kD

  • 推荐稀释比

    IHC 1:100-200;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthetic Peptide of GRIK2 (GluR6) AA range: 119-169

  • 特异性

    GRIK2(GluR6) protein(A240) detects endogenous levels of GRIK2(GluR6)

  • 基因名称

    GRIK2

  • 蛋白名称

    Glutamate receptor, ionotropic kainate 2 (Excitatory amino acid receptor 4) (EAA4) (Glutamate receptor 6) (GluR-6) (GluR6)

  • 别名

    Glutamate receptor, ionotropic kainate 2;Excitatory amino acid receptor 4;EAA4;Glutamate receptor 6;GluR-6;GluR6;

  • Organism-1

    Human

  • 基因ID-1

    2898

  • SwissProt-1

    Q13002

  • Organism-2

    Mouse

  • SwissProt-2

    P39087

  • 背景

    Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.