FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
HIF-1β
反应性
Human,Mouse,Rat
应用
WB,IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
87kD
推荐稀释比
WB 1:1000-2000;IHC 1:200-500;IF 1:50-200
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Polyclonal
免疫原
Recombinant Protein of HIF-1β
特异性
The antibody detects endogenous HIF-1β protein.
基因名称
ARNT
蛋白名称
Aryl hydrocarbon receptor nuclear translocator
别名
ARNT;BHLHE2;Aryl hydrocarbon receptor nuclear translocator;ARNT protein;Class E basic helix-loop-helix protein 2;bHLHe2;Dioxin receptor, nuclear translocator;Hypoxia-inducible factor 1-beta;HIF-1-beta;HIF1-beta
Organism-1
Human
基因ID-1
405
SwissProt-1
P27540
Organism-2
Mouse
SwissProt-2
P53762
Organism-3
Rat
SwissProt-3
P41739
背景
This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013],
细胞定位
Nucleus.
