FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
HSC70
反应性
Human,Mouse,Rat
应用
WB,IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70-72kD
推荐稀释比
WB 1:500-1:2000;IHC:1:50-300;IF 1:50-200
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the Internal region of human HSC 70. AA range: 588-638
特异性
The antibody detects endogenous HSC 70 protein.
基因名称
HSPA8
蛋白名称
Heat shock cognate 71 kDa protein
别名
HSPA8;HSC70;HSP73;HSPA10;Heat shock cognate 71 kDa protein;Heat shock 70 kDa protein 8
Organism-1
Human
基因ID-1
3312
SwissProt-1
P11142
Organism-2
Mouse
SwissProt-2
P63017
Organism-3
Rat
SwissProt-3
P63018
背景
This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],
细胞定位
Cytoplasm. Melanosome. Nucleus, nucleolus. Cell membrane. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock.
