FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
KChIP3
反应性
Human,Rat,Mouse
应用
IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
29kD
推荐稀释比
IHC 1:100-200;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic Peptide of KChIP3 AA range: 169-219
特异性
KChIP3 protein(A250) detects endogenous levels of KChIP3
基因名称
KCNIP3
蛋白名称
Calsenilin (A-type potassium channel modulatory protein 3) (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3)
别名
KCNIP3;CSEN;DREAM;KCHIP3;Calsenilin;A-type potassium channel modulatory protein 3;DRE-antagonist modulator;DREAM;Kv channel-interacting protein 3;KChIP3
Organism-1
Human
基因ID-1
30818
SwissProt-1
Q9Y2W7
Organism-2
Mouse
SwissProt-2
Q9QXT8
Organism-3
Rat
SwissProt-3
Q9JM47
背景
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Cell membrane ; Lipid-anchor . Endoplasmic reticulum . Golgi apparatus . Nucleus . Also membrane-bound, associated with the plasma membrane (PubMed:15485870). In the presence of PSEN2 associated with the endoplasmic reticulum and Golgi. The sumoylated form is present only in the nucleus. .
