KCNK4 (TRAAK) Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2607591

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商品描述
  • 靶点-Target

    KCNK4

  • 反应性

    Human,Rat,Mouse

  • 应用

    IHC,IF

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    43kD

  • 推荐稀释比

    IHC 1:100-200;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthetic Peptide of KCNK4 (TRAAK) AA range: 38-88

  • 特异性

    KCNK4(TRAAK) protein(A238) detects endogenous levels of KCNK4(TRAAK)

  • 基因名称

    KCNK4

  • 蛋白名称

    Potassium channel subfamily K member 4 (TWIK-related arachidonic acid-stimulated potassium channel protein) (TRAAK) (Two pore potassium channel KT4.1) (Two pore K(+) channel KT4.1)

  • 别名

    KCNK4;TRAAK;Potassium channel subfamily K member 4;TWIK-related arachidonic acid-stimulated potassium channel protein;TRAAK;Two pore potassium channel KT4.1;Two pore K;+;channel KT4.1

  • Organism-1

    Human

  • 基因ID-1

    50801

  • SwissProt-1

    Q9NYG8

  • Organism-2

    Mouse

  • SwissProt-2

    O88454

  • 背景

    This gene encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons. Alternate splicing results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream testis expressed 40 (TEX40) gene, as represented in GeneID: 106780802. [provided by RefSeq, Nov 2015],

  • 细胞定位

    Cell membrane ; Multi-pass membrane protein .