KCNN2 (SK2) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2607589
- 产品信息
商品描述
靶点-Target
KCNN2
反应性
Human,Rat,Mouse
应用
WB,IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70,26kD
推荐稀释比
WB 1:1000-2000;IHC 1:100-200;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic Peptide of KCNN2 (SK2)
特异性
KCNN2(SK2) protein(A244) detects endogenous levels of KCNN2(SK2)
别名
YM3565
Organism-1
Human
基因ID-1
3781
SwissProt-1
Q6PJI0
背景
potassium calcium-activated channel subfamily N member 2(KCNN2) Homo sapiens Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013],
细胞定位
smooth endoplasmic reticulum,plasma membrane,cell surface,integral component of membrane,Z disc,T-tubule,neuronal cell body,dendritic spine,





