KCNN2 (SK2) Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2607589

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商品描述
  • 靶点-Target

    KCNN2

  • 反应性

    Human,Rat,Mouse

  • 应用

    WB,IHC,IF

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    70,26kD

  • 推荐稀释比

    WB 1:1000-2000;IHC 1:100-200;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthetic Peptide of KCNN2 (SK2)

  • 特异性

    KCNN2(SK2) protein(A244) detects endogenous levels of KCNN2(SK2)

  • 别名

    YM3565

  • Organism-1

    Human

  • 基因ID-1

    3781

  • SwissProt-1

    Q6PJI0

  • 背景

    potassium calcium-activated channel subfamily N member 2(KCNN2) Homo sapiens Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013],

  • 细胞定位

    smooth endoplasmic reticulum,plasma membrane,cell surface,integral component of membrane,Z disc,T-tubule,neuronal cell body,dendritic spine,