KCNN3 (SK3) Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2607588

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商品描述
  • 靶点-Target

    KCNN3

  • 反应性

    Human,Rat

  • 应用

    IHC,IF

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    82kD

  • 推荐稀释比

    IHC 1:100-200;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthetic Peptide of KCNN3 (SK3) AA range: 161-211

  • 特异性

    KCNN3(SK3) protein(A246) detects endogenous levels of KCNN3(SK3)

  • 基因名称

    KCNN3

  • 蛋白名称

    Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa 3) (SKCa3) (KCa2.3)

  • 别名

    Small conductance calcium-activated potassium channel protein 3;SK3;SKCa 3;SKCa3;KCa2.3;

  • Organism-1

    Human

  • 基因ID-1

    3782

  • SwissProt-1

    Q9UGI6

  • Organism-2

    Mouse

  • SwissProt-2

    P58391

  • Organism-3

    Rat

  • SwissProt-3

    P70605

  • 背景

    potassium calcium-activated channel subfamily N member 3(KCNN3) Homo sapiens Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript v

  • 细胞定位

    Membrane; Multi-pass membrane protein.