FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Kv1.8
反应性
Human,Mouse
应用
WB,IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
58kD
推荐稀释比
WB 1:1000-2000;IHC 1:100-200;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic Peptide of Kv1.8 AA range: 194-244
特异性
Kv1.8 protein(A258) detects endogenous levels of Kv1.8
基因名称
KCNA10
蛋白名称
Potassium voltage-gated channel subfamily A member 10 (Voltage-gated potassium channel subunit Kv1.8)
别名
Potassium voltage-gated channel subfamily A member 10;Voltage-gated potassium channel subunit Kv1.8;
Organism-1
Human
基因ID-1
3744
SwissProt-1
Q16322
背景
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA
细胞定位
Membrane ; Multi-pass membrane protein .
