- 产品信息
商品描述
靶点-Target
Kv11.3
反应性
Human,Rat,Mouse
应用
WB,IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
83135kD
推荐稀释比
WB 1:1000-2000;IHC 1:100-200;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic Peptide of Kv11.3. AA range 1130-1180
特异性
Kv11.3 protein(A263) detects endogenous levels of Kv11.3
基因名称
KCNH7
蛋白名称
Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (hERG-3) (Voltage-gated potassium channel subunit Kv11.3)
别名
Potassium voltage-gated channel subfamily H member 7;Ether-a-go-go-related gene potassium channel 3;ERG-3;Eag-related protein 3;Ether-a-go-go-related protein 3;hERG-3;Voltage-gated potassium channel subunit Kv11.3;
Organism-1
Human
基因ID-1
90134
SwissProt-1
Q9NS40
Organism-2
Mouse
SwissProt-2
Q9ER47
Organism-3
Rat
SwissProt-3
O54852
背景
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms. [provided by RefSeq, Jul 2008],
细胞定位
Membrane; Multi-pass membrane protein.





